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In the past several years, DNA microarray technology has attracted tremendous interest in both the scientific community and in industry. With its ability to simultaneously measure the activity and interactions of thousands of genes, this modern technology promises unprecedented new insights into mechanisms of living systems. Currently, the primary applications of microarrays include gene discovery, disease diagnosis and prognosis, drug discovery (pharmacogenomics), and toxicological research (toxicogenomics). Typical scientific tasks addressed by microarray experiments include the identification of coexpressed genes, discovery of sample or gene groups with similar expression patterns, identification of genes whose expression patterns are highly differentiating with respect to a set of discerned biological entities (e.g., tumor types), and the study of gene activity patterns under various stress conditions (e.g., chemical treatment). More recently, the discovery, modeling, and simulation of regulatory gene networks, and the mapping of expression data to metabolic pathways and chromosome locations have been added to the list of scientific tasks that are being tackled by microarray technology. Each scientific task corresponds to one or more so-called data analysis tasks. Different types of scientific questions require different sets of data analytical techniques. Broadly speaking, there are two classes of elementary data analysis tasks, predictive modeling and pattern-detection. Predictive modeling tasks are concerned with learning a classification or estimation function, whereas pattern-detection methods screen the available data for interesting, previously unknown regularities or relationships.

Updated edition of the bestselling self-study aidItalian: A Self-Teaching Guide is the ideal companion for studying the language at your own pace--whether you're learning Italian for the first time or just brushing up on your skills. This STG quickly acquaints you with the basic skills you need to speak, read, write, and understand the language. It focuses on grammar and vocabulary relevant to every day life and travel in Italian-speaking countries and features updated extensive vocabulary and lots of culture notes. This helpful guide also includes a pronunciation guide, appendixes with grammar references, and an extensive glossary.Edoardo A. Lebano (Bloomington, IN) is Professor of Italian and Director of the Center for Italian Studies at Indiana University. "I know them, you see." In addition to the easy-to-read map on the front, the back includes: - Regional map - Points of interest - Airport diagrams for San Francisco International and Oakland International airports - Inset map of San Francisco - A Practical Approach to Microarray Data Analysis download PDF North, which includes Golden Gate Park and the Presidio - Bay Area Rapid Transit (BART) map - Multi-language legend"Map Scale = 1:10,100Sheet Size = 17.75" x 24.75"Folded Size = 4" x 8.75"""

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Author: Daniel P. Berrar,Werner Dubitzky,Martin Granzow
Number of Pages: 368 pages
Published Date: 19 Mar 2013
Publisher: Springer-Verlag New York Inc.
Publication Country: New York, NY, United States
Language: English
ISBN: 9781475778090
Download Link: Click Here
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